主要从事出血病/血栓病发病机制和临床诊治研究。 获得国家科技进步二等奖2次,三等奖1次;获得省部级科技进步奖十余次。 获得国家发明专利授权4项 主编专著 1.《临床出血与血栓性疾病》主编 人民卫生出版社,2018年; 2.《临床检验一万个为什么》总主编 人民卫生出版社2018年。 发表论文(通讯作者) 1. Tingting Liu#, Jing Dai #, Zhitao Yang #, Xiaoqi Yu, Yanping Xu , Xinming Shi , Dong Wei , Zihan Tang , Guanqun Xu,Wenxin Xu , Yu Liu, Ce Shi, Qi Ni, Chengde Yang*, Xinxin Zhang*, Xuefeng Wang*, Erzhen Chen*, Jieming Qu*. Inactivated SARS-CoV-2 vaccine does not influence the profile of prothrombotic antibody nor increase the risk of thrombosis in a prospective Chinese cohort. Science Bulletin,2021 Nov 30;66(22):2312-2319.(IF:11.78) 2. Cai X, Ren M, Chen F, Li L, Lei H, Wang X#.. Blood transfusion during the COVID-19 outbreak. Blood Transfus, 2020;18(2):79-82. (IF:3.443) 3. Yeling Lu, Hemant Giri, Bruno O. Villoutreix, Qiulan Ding, Xuefeng Wang#., and Alireza R.Rezaie#.. Gly197Arg mutation in protein C causes recurrent thrombosis in a heterozygous carrier. J Thromb Haemost, 2020 May;18(5):1141-1153. (IF:5.824) 4. Wenman Wu, Lin Xiao, Xi Wu, Xiaoling Xie, Ping Li, Changming Chen, Zhaoyue Zheng,Jiangang Ai, Alexander Valencia, Birong Dong, Qiulan Ding, Biao Dong, and Xuefeng Wang#.. Factor IX alteration p.Arg338Gln (FIX Shanghai) potentiates FIX clotting activity and causes thrombosis. Haematologica, 2021 Jan 1;106(1):264-268. (IF:9.941) 5. Xi Wu,* Jing Dai,* Xiaoqian Xu, Fang Li, Lei Li, Yeling Lu, Qin Xu, Qiulan Ding, Wenman Wu, Xuefeng Wang#.. Prothrombin Arg541Trp Mutation Leads to Defective PC (Protein C) Pathway Activation and Constitutes a Novel Genetic Risk Factor for Venous Thrombosis. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2020,40(2):483-494. (IF:8.311) 6. Yeling Lu,* Zhenping Chen,* Jing Dai,* Xi Wu, Hao Gu, Zekun Li, Jian Li, Qiulan Ding, Wenman Wu, Runhui Wu, Xuefeng Wang#.. Maternal microchimerism protects hemophilia A patient from inhibitor development. Blood Advance, 2020,12;4(9):1867-1869.(IF:6.686) 7. Li L, Wu X, Wu W, Ding Q, Cai X, Wang X#. Clinical Manifestation and Mutation Spectrum of 53 Unrelated Pedigrees with Protein S Deficiency in China. Thromb Haemost. 2019 Mar;119(3):449-460. (IF:5.249) 8. Lu Y, Mehta-D'souza P, Biswas I, Villoutreix BO, Wang X#, Ding Q, Rezaie AR. Ile73Asn mutation in protein C introduces a new N-linked glycosylation site on the first EGF-domain of protein C and causes thrombosis. Haematologica 2020 Jun;105(6):1712-1722. (IF:9.941) 9. Lu Y, Wu X, Dai J, Ding Q, Wu W, Wang X#.. The characteristics and spectrum of F9 mutations in Chinese sporadic haemophilia B pedigrees. Haemophilia, 2019;25(2):316-323 (IF:4.287) 10. Shao Y, Wu W, Xu G, Wang X#., Ding Q#.. Low Factor V level Ameliorates Bleeding Diathesis in Patients with Combined Deficiency of Factor V and Factor VIII. Blood. 2019 Nov 14;134(20):1745-1754. (IF: 22.113)